Practical ways to deal with the high burden of cardiovascular disease in hemodialysis patients
- PMID: 16612461
- PMCID: PMC11060401
- DOI: 10.1590/s1516-31802006000100008
Practical ways to deal with the high burden of cardiovascular disease in hemodialysis patients
Abstract
Cardiovascular disease is the main cause of death among hemodialysis patients. Although uremia by itself may be considered to be a cardiovascular risk factor, a significant proportion of dialysis patients die because of cardiovascular disease not directly attributable to uremia. Indeed, many of the cardiovascular diseases and cardiovascular risk factors in these patients are common to those occurring in the general population and are amenable to intervention. Lack of proper medical care during the early stages of renal insufficiency and present-day dialysis routines, by failing to correct hypertension, hypervolemia and left ventricular hypertrophy in many patients, may also add to the cardiovascular burden. The author suggests that, in addition to early treatment and referral to a specialist, chronic renal failure patients should undergo intensive cardiovascular screening and treatment, and correction of cardiovascular risk factors based on guidelines established for the general population.
CONTEXTO:: A doença cardiovascular é a principal causa de morte em pacientes tratados por hemodiálise crônica. Embora a uremia por si só possa ser considerada um fator de risco cardiovascular, uma proporção significativa de pacientes tratados por diálise morre devido a problemas cardiovasculares não diretamente atribuíveis à uremia. De fato, muitas das alterações cardiovasculares e fatores de risco cardiovascular observados em pacientes renais crônicos são comuns aos que ocorrem na população geral e podem ser controlados por medidas de comprovada eficácia em indivíduos não-doentes renais. A falta de cuidados médicos apropriados durante as fases iniciais da insuficiência renal e os atuais métodos e rotinas empregadas na diálise, por não conseguirem garantir o controle adequado da hipertensão, hipervolemia e da hipertrofia ventricular, em muitos pacientes, contribuem para o aumento da pletora de problemas cardiovasculares. O autor sugere que, em adição à instituição de tratamento adequado e envio precoce aos especialistas, doentes renais crônicos devam ser submetidos a avaliação cardiovascular minuciosa visando o tratamento das alterações cardiovasculares e correção dos fatores de risco baseados nas diretivas estabelecidas para a população geral.
Conflict of interest statement
Similar articles
-
Cardiac and cerebrovascular disease in chronic uremia.Am J Kidney Dis. 1993 Jan;21(1):77-80. doi: 10.1016/s0272-6386(12)80726-8. Am J Kidney Dis. 1993. PMID: 8418631 Review.
-
Intensive Hemodialysis, Left Ventricular Hypertrophy, and Cardiovascular Disease.Am J Kidney Dis. 2016 Nov;68(5S1):S5-S14. doi: 10.1053/j.ajkd.2016.05.025. Am J Kidney Dis. 2016. PMID: 27772643 Review.
-
Options in dialysis therapy: significance of cardiovascular findings.Kidney Int Suppl. 1993 Feb;40:S85-91. Kidney Int Suppl. 1993. PMID: 8445844 Review.
-
Left ventricular hypertrophy is a risk factor independent of hypertension in survival of hemodialyzed patients.Ren Fail. 2002 Mar;24(2):175-86. doi: 10.1081/jdi-120004094. Ren Fail. 2002. PMID: 12071591
-
Cardiovascular problems in dialysis patients: impact on survival.Adv Perit Dial. 2010;26:47-52. Adv Perit Dial. 2010. PMID: 21348379 Review.
References
-
- Sarnak MJ, Levey AS, Schoolwerth AC, et al. Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention. Circulation. 2003;108:2154–2169. - PubMed
-
- Zatz R, Romao JE, Jr, Noronha IL. Nephrology in Latin America, with special emphasis on Brazil. Kidney Int Suppl. 2003;(83):S131–S134. - PubMed
-
- Locatelli F, Del Vecchio L, Manzoni C. Morbidity and mortality on maintenance haemodialysis. Nephron. 1998;80(4):380–400. - PubMed
-
- De Lima JJ, Sabbaga E, Vieira ML, et al. Coronary angiography is the best predictor of events in renal transplant candidates compared with noninvasive testing. Hypertension. 2003;42(3):263–268. - PubMed
-
- De Lima JJ, Gowdak LH, Vieira ML, de Paula FJ, Ramires JA, Krieger EM. Diabetes increases cardiovascular morbidity and mortality in patients with end-stage renal disease even in the absence of significant coronary artery disease. [Abstract] Circulation. 2003;108(17 Suppl):S719.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical