Burn wound infections
- PMID: 16614255
- PMCID: PMC1471990
- DOI: 10.1128/CMR.19.2.403-434.2006
Burn wound infections
Abstract
Burns are one of the most common and devastating forms of trauma. Patients with serious thermal injury require immediate specialized care in order to minimize morbidity and mortality. Significant thermal injuries induce a state of immunosuppression that predisposes burn patients to infectious complications. A current summary of the classifications of burn wound infections, including their diagnosis, treatment, and prevention, is given. Early excision of the eschar has substantially decreased the incidence of invasive burn wound infection and secondary sepsis, but most deaths in severely burn-injured patients are still due to burn wound sepsis or complications due to inhalation injury. Burn patients are also at risk for developing sepsis secondary to pneumonia, catheter-related infections, and suppurative thrombophlebitis. The introduction of silver-impregnated devices (e.g., central lines and Foley urinary catheters) may reduce the incidence of nosocomial infections due to prolonged placement of these devices. Improved outcomes for severely burned patients have been attributed to medical advances in fluid resuscitation, nutritional support, pulmonary and burn wound care, and infection control practices.
Figures




References
-
- Abraham, E., and A. A. Freitas. 1989. Hemorrhage produces abnormalities in lymphocyte function and lymphokine generation. J. Immunol. 142:899-906. - PubMed
-
- Acikel, C., O. Oncul, E. Ulkur, I. Bayram, B. Celikoz, and S. Cavuslu. 2003. Comparison of silver sulfadiazine 1%, mupirocin 2%, and fusidic acid 2% for topical antibacterial effect in methicillin-resistant staphylococci-infected, full-skin thickness rat burn wounds. J. Burn Care Rehabil. 24:37-41. - PubMed
-
- Agnihotri, N., V. Gupta, and R. M. Joshi. 2004. Aerobic bacterial isolates from burn wound infections and their antibiograms—a five-year study. Burns 30:241-243. - PubMed
-
- Alexander, J. W. 1990. Mechanism of immunologic suppression in burn injury. J. Trauma 30:S70-S75. - PubMed
-
- Altman, L. C., C. T. Furukawa, and S. J. Klebanoff. 1977. Depressed mononuclear leukocyte chemotaxis in thermally injured patients. J. Immunol. 119:199-205. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical