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. 2006 Apr;21(2):224-8.
doi: 10.3346/jkms.2006.21.2.224.

Surgical resection of recurrent lung cancer in patients following curative resection

Hyoung Soo Kim  1 , Hoseok I, Yong Soo Choi, Kwhanmien Kim, Young Mog Shim, Jhingook Kim
Affiliations

Surgical resection of recurrent lung cancer in patients following curative resection

Hyoung Soo Kim et al. J Korean Med Sci. 2006 Apr.

Abstract

We reviewed our experience with resection of recurrent lung cancer to evaluate the benefit and risk of the procedure. From December 1994 to December 2003, 29 consecutive patients underwent pulmonary resections for recurrent lung cancer. The mean duration from the first resection to second surgery was 25.4+/-15.1 months for the definite 2nd primary lung cancer (n=20) and 8.9+/-5.7 months for metastatic lung cancer (n=9). The procedures at the second operations were completion-pneumonectomy in 11 patients, lobectomy in 5 patients, wedge resection in 12 patients and resection and anastomosis of trachea in 1 patient. Morbidity was observed in 6 (21%) of the patients and the in-hospital mortality was two patients (7%) after the repeated lung resection. Tumor recurrence after reoperation was observed in 14 patients (48%). The actuarial 5-yr survival rate was 69% and the 5-yr disease free rate following reoperation was 44%. No significant difference was found in overall survival and disease free survival between the 2nd primary lung cancer group and the metastatic lung cancer group. The recurrence rate following reoperation was significantly different between the wedge resection group and lobectomy/completion pneumonectomy group (p=0.008), but the survival rate was not significantly different (p=0.41). Surgical intervention for recurrent lung cancers can be performed with acceptable mortality and morbidity. If tolerable, completion pneumonectomy or lobectomy is recommended for resection of recurrent lung cancer.

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Figures

Fig. 1
Fig. 1
Actuarial survival for recurrent lung cancer with 2nd primary and metastatic tumor after the second operations.
Fig. 2
Fig. 2
Cumulative disease free rates of recurrent lung cancer with 2nd primary and metastatic tumor.
Fig. 3
Fig. 3
Cumulative disease free rates for patients with lobectomy/c-pneumonectomy and wedge resection.
See this image and copyright information in PMC

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