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doi: 10.1016/j.cell.2006.03.016.
NoCut: cytokinesis in check
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- PMID: 16615883
- DOI: 10.1016/j.cell.2006.03.016
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Comment
NoCut: cytokinesis in check
Cell.
.
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Abstract
In this issue of Cell, Norden et al. (2006) describe a new pathway, NoCut, that links the completion of chromosome segregation to the onset of cytokinesis in budding yeast. In NoCut, Aurora kinase (Ipl1) at the spindle midzone negatively regulates cytokinesis through two proteins previously identified to be involved in cell polarity, Boi1 and Boi2.
Comment on
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The NoCut pathway links completion of cytokinesis to spindle midzone function to prevent chromosome breakage.Cell. 2006 Apr 7;125(1):85-98. doi: 10.1016/j.cell.2006.01.045. Cell. 2006. PMID: 16615892
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