Emerging patterns in complement-mediated pathogen recognition
- PMID: 16615887
- DOI: 10.1016/j.cell.2006.03.018
Emerging patterns in complement-mediated pathogen recognition
Abstract
Protection from acute infection requires an immediate response by the host innate immune system. Two recent Cell papers, including one in this issue, provide new insight into the role of the complement system in response to blood-borne pathogens.
Comment on
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CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens.Cell. 2006 Mar 10;124(5):915-27. doi: 10.1016/j.cell.2005.12.039. Cell. 2006. PMID: 16530040
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A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q.Cell. 2006 Apr 7;125(1):47-58. doi: 10.1016/j.cell.2006.01.046. Cell. 2006. PMID: 16615889
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