Shedding UV light on the phase problem
- PMID: 16615902
- DOI: 10.1016/j.str.2006.03.004
Shedding UV light on the phase problem
Abstract
In this issue of Structure, Nanao and Ravelli (2006) describe the use of UV-induced radiation damage (UV-RIP) to solve the phase problem for proteins, employing single-wavelength X-ray radiation, without the need for derivatization. This should also permit data collection for many proteins on home sources, without travel to a synchrotron.
Comment on
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Phasing macromolecular structures with UV-induced structural changes.Structure. 2006 Apr;14(4):791-800. doi: 10.1016/j.str.2006.02.007. Structure. 2006. PMID: 16615919
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