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Meta-Analysis
. 2005 Sep;2(3):230-8.
doi: 10.1111/j.1742-4801.2005.00131.x.

A liquid film-forming acrylate for peri-wound protection: a systematic review and meta-analysis (3M Cavilon no-sting barrier film)

Jan Schuren  1 , Anja Becker, R Gary Sibbald
Affiliations
Meta-Analysis

A liquid film-forming acrylate for peri-wound protection: a systematic review and meta-analysis (3M Cavilon no-sting barrier film)

Jan Schuren et al. Int Wound J. 2005 Sep.

Abstract

To undertake a systematic review of all reliable evaluations of the clinical performance and cost-effectiveness of a film-forming liquid acrylate in the protection of the chronic ulcer peri-wound skin. Results from searches were scrutinised by two reviewers to identify possible randomised controlled trials and full reports of these were obtained. Details of eligible studies were extracted and summarised independently by two reviewers using a data extraction sheet. Meta-analysis was used to combine the results of trials where the interventions and outcome measures were sufficiently similar. A total of nine eligible studies were identified. The review reveals that a liquid-film forming acrylate (Cavilon no-sting barrier film, 3M, Minneapolis, MN, USA) is a safe and effective skin barrier to protect the peri-wound area of chronic ulcers. There is no difference between the protective properties of different barrier methods that are used to protect the peri-wound skin around chronic ulcers. Compared with no treatment or a placebo, this liquid film-forming acrylate has a significant impact on the integrity of the peri-wound skin. In addition, it has significant benefits in terms of pain control and patient comfort, and its use may reduce nursing time.

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Conflict of interest statement

Both reviewers are employed by 3M, Germany. Some of the research included in this review was supported by educational grants from 3M Company. Dr Sibbald is a professor of medicine and public health sciences at the University of Toronto. He has been an investigator, consultant and speaker for the 3M Company.

Figures

Figure 1
Figure 1
Product performance: erythema/maceration control (continuous data).
Figure 2
Figure 2
Product performance: erythema/maceration control (dichotomous data).
Figure 3
Figure 3
Wound healing.
Figure 4
Figure 4
Application time.
Figure 5
Figure 5
Pain and patient comfort.
Figure 6
Figure 6
Ease of application.
See this image and copyright information in PMC

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