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Case Reports
. 2005 Sep;2(3):253-7.
doi: 10.1111/j.1742-4801.2005.00120.x.

Wound conditioning of a deep tissue defect including exposed bone after tumour excision using PROMOGRAN* Matrix, a protease-modulating matrix

Anne-Kathrin Tausche  1 , Günther Sebastian
Affiliations
Case Reports

Wound conditioning of a deep tissue defect including exposed bone after tumour excision using PROMOGRAN* Matrix, a protease-modulating matrix

Anne-Kathrin Tausche et al. Int Wound J. 2005 Sep.

Abstract

A case study reporting on the successful treatment of a patient affected by a basal cell carcinoma is submitted. Because the carcinoma had infiltrated deeply, a wide excision was necessary, including the removal of bone tissue. The deep tissue defect was treated with PROMOGRAN* Matrix, a protease-modulating matrix, to promote granulation and ensure that the skin graft do survive and heal successfully. In this case study, a rapid development of granulation tissue on the exposed surface of the bone was observed. The benefits of the dressing enabled a successful split-thickness skin grafting to be carried out which gave very good aesthetic and functional results.

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Figures

Figure 1
Figure 1
Initial diagnosis of tumour.
Figure 2
Figure 2
Histopathology [HE‐staining, magnification: (A) 60:1, (B) 200:1].
Figure 3
Figure 3
(a and b) Second resection (micrographic‐controlled surgery).
Figure 4
Figure 4
(a) Clinical finding prior to local treatment. (b) Central areas of granulation tissue (after 3 weeks).
Figure 5
Figure 5
(a) Clinical finding before split skin graft (after 10 weeks). (b) Result after split‐thickness skin graft.
See this image and copyright information in PMC

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