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Review
. 2006 Apr;24(4):359-61.
doi: 10.1016/j.immuni.2006.03.009.

Multiple paths to multispecificity

Roy A Mariuzza  1
Affiliations
Free article
Review

Multiple paths to multispecificity

Roy A Mariuzza. Immunity. 2006 Apr.
Free article

Abstract

The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site.

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