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. 2006 May 15;42(10):1443-7.
doi: 10.1086/503570. Epub 2006 Apr 11.

The poor prognosis of central nervous system cryptococcosis among nonimmunosuppressed patients: a call for better disease recognition and evaluation of adjuncts to antifungal therapy

Ismail Zafer Ecevit  1 , Cornelius J Clancy, Ilona M Schmalfuss, M Hong Nguyen
Affiliations

The poor prognosis of central nervous system cryptococcosis among nonimmunosuppressed patients: a call for better disease recognition and evaluation of adjuncts to antifungal therapy

Ismail Zafer Ecevit et al. Clin Infect Dis. .

Abstract

We describe 9 nonimmunosuppressed patients with central nervous system cryptococcosis. Morbidity and mortality were high, especially among patients with cerebral infarcts. This was attributed to delayed diagnosis and apparent sequelae of overwhelming host immune responses. We present clues suggesting the diagnosis. Increased recognition and timely diagnosis of this condition may improve outcomes.

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Comment in

  • Cryptococcosis: we should do better!
    Antinori S. Antinori S. Clin Infect Dis. 2006 Oct 1;43(7):948-9; author reply 949-50. doi: 10.1086/507541. Clin Infect Dis. 2006. PMID: 16941382 No abstract available.

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