UV-induced reversion of a temperature-sensitive late mutant of simian virus 40 to a wild-type phenotype
- PMID: 166205
- PMCID: PMC354652
- DOI: 10.1128/JVI.16.1.214-216.1975
UV-induced reversion of a temperature-sensitive late mutant of simian virus 40 to a wild-type phenotype
Abstract
Irradiation of a simian virus 40 temperature-sensitive late mutant before infection of CV1 cells produces viruses that are phenotypically wild-type revertants. This probably occurs through suppression rather than true reversion because the revertants are produced at relatively high frequency and still have some properties of the original temperature-sensitive virus.
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