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Review
. 2006 Jun;18(3):284-90.
doi: 10.1016/j.ceb.2006.03.002. Epub 2006 Apr 18.

The road much traveled: trafficking in the cell nucleus

Stanislaw A Gorski  1 , Miroslav Dundr, Tom Misteli
Affiliations
Review

The road much traveled: trafficking in the cell nucleus

Stanislaw A Gorski et al. Curr Opin Cell Biol. 2006 Jun.

Abstract

Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function.

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