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Review
. 2006:577:274-87.
doi: 10.1007/0-387-32957-9_20.

The polyomavirus, JCV and its involvement in human disease

Kamel Khalili  1 , Jennifer Gordon, Martyn K White
Affiliations
Review

The polyomavirus, JCV and its involvement in human disease

Kamel Khalili et al. Adv Exp Med Biol. 2006.

Abstract

The human neurotropic polyomavirus, JC virus (JCV), is the etiologic agent of progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease of the central nervous system that occurs mainly in immunosuppressed patients. JCV has also been found to be associated with human tumors of the brain and other organs. In this chapter, we describe JC virus and its role in human diseases.

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