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Comment
. 2006 Apr 21;22(2):149-50.
doi: 10.1016/j.molcel.2006.04.001.

XPB: An essential helicase involved in both transcription and repair of DNA

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XPB: An essential helicase involved in both transcription and repair of DNA

Joanna Timmins et al. Mol Cell. .
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Abstract

Helicases are molecular motors known to unwind double-stranded DNA. In a recent issue of Molecular Cell, Fan et al. (2006) revealed the core structure of XPB helicase, a component of transcription factor IIH, and proposed a mechanism for its dual role in transcription and nucleotide excision repair.

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