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Comment
. 2006 Apr 21;22(2):155-6.
doi: 10.1016/j.molcel.2006.04.004.

Two-step selection of mRNAs in initiation of protein synthesis

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Comment

Two-step selection of mRNAs in initiation of protein synthesis

Vasili Hauryliuk et al. Mol Cell. .
Free article

Abstract

In a recent issue of Molecular Cell, Studer and Joseph (2006) clarified the molecular basis of the "standby model" and demonstrated how two-step binding of mRNAs to the small ribosomal subunit depends on initiator tRNA and initiation factors, with far-reaching implications for posttranscriptional regulation of gene expression.

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