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Case Reports
. 2006 Aug 30;30(6):1143-5.
doi: 10.1016/j.pnpbp.2006.03.015. Epub 2006 Apr 24.

Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting

Affiliations
Case Reports

Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting

Chi-Un Pae. Prog Neuropsychopharmacol Biol Psychiatry. .

Abstract

The antagonism of 5-HT3 receptor by mirtazapine results in an antiemetic effect, suggesting that mirtazapine could be considered a successful antiemetic agent in patients suffering from severe nausea and vomiting. There have been several reports of successful mirtazapine treatment for nausea or vomiting from secondary causes but cases of primary severe nausea and vomiting are still lacking, in particular, there are no reported cases in Asians. The authors report two cases with severe nausea and vomiting that were dramatically treated with mirtazapine in the Korean population.

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