Minimising ventilator induced lung injury in preterm infants
- PMID: 16632652
- PMCID: PMC2672704
- DOI: 10.1136/adc.2005.082271
Minimising ventilator induced lung injury in preterm infants
Abstract
Ventilator induced lung injury continues to occur at an unacceptably high rate, which is inversely related to gestational age. Although the "new BPD" may not be entirely avoidable in the extremely premature infant, recognition of risk factors and adoption of an appropriate ventilatory strategy, along with continuous real time monitoring, may help to minimise lung damage. This paper will review the pathogenesis of ventilator induced lung injury and strategies that may mitigate it.
Conflict of interest statement
Competing interests: none declared
References
-
- Northway W H, Rosan R C, Porter D Y. Pulmonary disease following respirator therapy of hyaline membrane disease. Bronchopulmonary dysplasia. N Engl J Med 1967276357–368. - PubMed
-
- Philip A G S. Oxygen plus pressure plus time: the etiology of bronchopulmonary dysplasia. Pediatrics 19755544–50. - PubMed
-
- Jobe A H. The new BPD: an arrest of lung development. Pediatr Res 199946641–643. - PubMed
-
- Attar M A, Donn S M. Mechanism of ventilator‐induced lung injury in premature infants. Semin Neonatol 20027353–360. - PubMed
-
- Dreyfuss D, Saumon G. Ventilator‐induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 1998157294–323. - PubMed