Inflammatory bowel disease
- PMID: 16632672
- PMCID: PMC2082730
- DOI: 10.1136/adc.2005.080481
Inflammatory bowel disease
Abstract
Twenty five per cent of inflammatory bowel disease presents in childhood. Growth and nutrition are key issues in the management with the aim of treatment being to induce and then maintain disease remission with minimal side effects. Only 25% of Crohn's disease presents with the classic triad of abdominal pain, weight loss, and diarrhoea. Most children with ulcerative colitis have blood in the stool at presentation. Inflammatory markers are usually although not invariably raised at presentation (particularly in Crohn's disease). Full investigation includes upper gastrointestinal endoscopy and ileocolonoscopy. Treatment requires multidisciplinary input as part of a clinical network led by a paediatrician with special expertise in the management of the condition.
Conflict of interest statement
Competing interests: none declared
Similar articles
-
Advances in inflammatory bowel diseases in children.Minerva Pediatr. 2012 Jun;64(3):257-70. Minerva Pediatr. 2012. PMID: 22555319 Review.
-
Paediatric inflammatory bowel disease in New Zealand.N Z Med J. 2008 Oct 3;121(1283):19-34. N Z Med J. 2008. PMID: 18841182
-
Chronic inflammatory bowel disease.Indian J Pediatr. 1994 Nov-Dec;61(6):655-63. doi: 10.1007/BF02751974. Indian J Pediatr. 1994. PMID: 7721370 Review. No abstract available.
-
Advances in Pediatric Inflammatory Bowel Disease.Adolesc Med State Art Rev. 2016 Spring;27(1):57-74. Adolesc Med State Art Rev. 2016. PMID: 27363233 Review. No abstract available.
-
[Inflammatory bowel disease: an overview].Med Monatsschr Pharm. 2013 Nov;36(11):402-8; quiz 409. Med Monatsschr Pharm. 2013. PMID: 24640117 Review. German.
Cited by
-
The reduction of faecal calprotectin during exclusive enteral nutrition is lost rapidly after food re-introduction.Aliment Pharmacol Ther. 2019 Sep;50(6):664-674. doi: 10.1111/apt.15425. Epub 2019 Jul 25. Aliment Pharmacol Ther. 2019. PMID: 31342536 Free PMC article.
-
Epidemiological analysis reveals a surge in inflammatory bowel disease among children and adolescents: A global, regional, and national perspective from 1990 to 2019 - insights from the China study.J Glob Health. 2023 Dec 1;13:04174. doi: 10.7189/jogh.13.04174. J Glob Health. 2023. PMID: 38037705 Free PMC article.
-
Diagnostic role of upper gastrointestinal endoscopy in patients with inflammatory bowel disease.Ghana Med J. 2007 Sep;41(3):144-5. Ghana Med J. 2007. PMID: 18470333 Free PMC article. No abstract available.
-
Multifocal neuromuscular hamartoma with smooth muscle and Schwannian components.BMJ Case Rep. 2024 Dec 22;17(12):e256041. doi: 10.1136/bcr-2023-256041. BMJ Case Rep. 2024. PMID: 39950659 Free PMC article.
-
Fecal M2-PK in children with Crohn's disease: a preliminary report.Dig Dis Sci. 2012 Aug;57(8):2166-70. doi: 10.1007/s10620-012-2215-3. Epub 2012 Jun 27. Dig Dis Sci. 2012. PMID: 22736014
References
-
- Loftus E V. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 20041261504–1517. - PubMed
-
- Sartor R B. Role of commensal enteric bacteria in the pathogenesis of immune‐mediated intestinal inflammation: lessons from animal models and implications for translational research. J Pediatr Gastroenterol Nutr 200540(suppl 1)S30–S31. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources