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Review
. 2006 Apr;11(2):100-12; discussion 112-3.
doi: 10.1111/j.1744-6155.2006.00048.x.

Formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): a critical review of the research

Kristen Wright  1 , Catherine Coverston, Mary Tiedeman, Jo Ann Abegglen
Affiliations
Review

Formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): a critical review of the research

Kristen Wright et al. J Spec Pediatr Nurs. 2006 Apr.

Abstract

Purpose: To summarize results of randomized controlled trials (RCTs) evaluating growth, cognitive, neurological, and visual development of term infants supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA).

Design and methods: The Boyack and Lookinland Methodological Quality Index (MQI) was used to evaluate data from RCTs identified from multiple data bases.

Results: Six of ten studies found the addition of DHA and ARA to have no significant effect on infant development.

Practice implications: More expensive formula with endogenous DHA and ARA is not necessary. Results from longer studies currently underway will be beneficial.

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