Formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): a critical review of the research
- PMID: 16635189
- DOI: 10.1111/j.1744-6155.2006.00048.x
Formula supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): a critical review of the research
Abstract
Purpose: To summarize results of randomized controlled trials (RCTs) evaluating growth, cognitive, neurological, and visual development of term infants supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA).
Design and methods: The Boyack and Lookinland Methodological Quality Index (MQI) was used to evaluate data from RCTs identified from multiple data bases.
Results: Six of ten studies found the addition of DHA and ARA to have no significant effect on infant development.
Practice implications: More expensive formula with endogenous DHA and ARA is not necessary. Results from longer studies currently underway will be beneficial.
Comment in
-
Sharing responsibilities to make evidence-based practice clinically feasible.J Spec Pediatr Nurs. 2006 Apr;11(2):77-9. doi: 10.1111/j.1744-6155.2006.00049.x. J Spec Pediatr Nurs. 2006. PMID: 16635186 No abstract available.
Similar articles
-
Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: a review of randomized controlled trials.Prostaglandins Leukot Essent Fatty Acids. 2009 Aug-Sep;81(2-3):151-8. doi: 10.1016/j.plefa.2009.05.003. Epub 2009 Jun 7. Prostaglandins Leukot Essent Fatty Acids. 2009. PMID: 19505812 Review.
-
Docosahexaenoic acid in red blood cells of term infants receiving two levels of long-chain polyunsaturated fatty acids.J Pediatr Gastroenterol Nutr. 2006 Mar;42(3):287-92. doi: 10.1097/01.mpg.0000189366.91792.64. J Pediatr Gastroenterol Nutr. 2006. PMID: 16540798 Clinical Trial.
-
Roles of long-chain polyunsaturated fatty acids in the term infant: developmental benefits.Neonatal Netw. 2007 Jul-Aug;26(4):229-34. doi: 10.1891/0730-0832.26.4.229. Neonatal Netw. 2007. PMID: 17710956 Review.
-
Docosahexaenoic acid and arachidonic acid enhance growth with no adverse effects in preterm infants fed formula.J Pediatr. 2002 May;140(5):547-54. doi: 10.1067/mpd.2002.123282. J Pediatr. 2002. PMID: 12032520 Clinical Trial.
-
Visual function in breast-fed term infants weaned to formula with or without long-chain polyunsaturates at 4 to 6 months: a randomized clinical trial.J Pediatr. 2003 Jun;142(6):669-77. doi: 10.1067/mpd.2003.213. J Pediatr. 2003. PMID: 12838196 Clinical Trial.
Cited by
-
Bioengineered Plants Can Be a Useful Source of Omega-3 Fatty Acids.Biomed Res Int. 2017;2017:7348919. doi: 10.1155/2017/7348919. Epub 2017 Feb 21. Biomed Res Int. 2017. PMID: 28316988 Free PMC article. Review.
-
Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice.Am J Physiol Endocrinol Metab. 2010 Apr;298(4):E862-70. doi: 10.1152/ajpendo.00491.2009. Epub 2009 Dec 29. Am J Physiol Endocrinol Metab. 2010. PMID: 20040693 Free PMC article.
-
High versus low medium chain triglyceride content of formula for promoting short-term growth of preterm infants.Cochrane Database Syst Rev. 2021 Feb 23;2(2):CD002777. doi: 10.1002/14651858.CD002777.pub2. Cochrane Database Syst Rev. 2021. PMID: 33620090 Free PMC article.
-
Erythrocyte membrane fatty acid content in infants consuming formulas supplemented with docosahexaenoic acid (DHA) and arachidonic acid (ARA): an observational study.Matern Child Nutr. 2010 Oct;6(4):338-46. doi: 10.1111/j.1740-8709.2009.00230.x. Matern Child Nutr. 2010. PMID: 21050388 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
