Pharmacogenetics: yeast lead the way
- PMID: 16638528
- DOI: 10.1016/j.chembiol.2006.03.001
Pharmacogenetics: yeast lead the way
Abstract
In this issue of Chemistry & Biology, Perlstein et al. use genetically diverse strains of yeast to study the genetic basis of differences in cellular responses to small molecules. Their results suggest that drug responses are regulated by a limited number of loci, and that this system can identify clusters of functionally similar molecules.
Comment on
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Revealing complex traits with small molecules and naturally recombinant yeast strains.Chem Biol. 2006 Mar;13(3):319-27. doi: 10.1016/j.chembiol.2006.01.010. Chem Biol. 2006. PMID: 16638537
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