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Review
. 2006 May;133(4):364-74.
doi: 10.1111/j.1365-2141.2006.06024.x.

The pathogenesis of immune thrombocytopaenic purpura

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Review

The pathogenesis of immune thrombocytopaenic purpura

Nichola Cooper et al. Br J Haematol. 2006 May.

Abstract

Immune thrombocytopaenic purpura (ITP) is an autoimmune bleeding disease that is rarely fatal. However, in many adults treatment is unsatisfactory, with as much morbidity from the immunosuppressive effects of treatment as from bleeding. Identifying the underlying disease process should help us to identify more targeted therapies and improve not only the treatment but also the quality of life of patients with this disorder.

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