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Review
. 2007 Mar;60(3):278-82.
doi: 10.1136/jcp.2006.036954. Epub 2006 Apr 27.

Three cases of pancreatic serous cystadenoma and endocrine tumour

Stella Blandamura  1 , Anna Parenti, Barbara Famengo, Alessandra Canesso, Paolo Moschino, Claudio Pasquali, Sara Pizzi, Vincenza Guzzardo, Vito Ninfo
Affiliations
Review

Three cases of pancreatic serous cystadenoma and endocrine tumour

Stella Blandamura et al. J Clin Pathol. 2007 Mar.

Abstract

Aims: To report three cases of serous cystadenoma and endocrine tumour in the same pancreas, to review the literature and to evaluate the clinicopathological features of the tumours.

Cases: Three women (71, 57 and 31 years old) were admitted to hospital, two for diseases unrelated to the pancreas and the third for increasing obstructive jaundice in von Hippel-Lindau disease. Preoperative examination showed two distinct lesions in the first patient and only cystic lesions in the other two.

Results: Histological examination of the pancreas showed one serous oligocystic adenoma associated with a benign, well-differentiated endocrine tumour, one serous oligocystic adenoma associated with an endocrine microadenoma, and a von Hippel-Lindau-related cystic neoplasm with a well-differentiated endocrine carcinoma.

Conclusions: Serous cystadenoma associated with endocrine tumour shows some clinicopathological differences with respect to the two tumours considered separately, and with respect to von Hippel-Lindau-related cases, although there is no convincing evidence at present to justify considering this association as a separate entity.

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