Viral contamination of fetal bovine serum used for tissue culture: risks and concerns
Affiliations
- PMID: 1665460
Item in Clipboard
Viral contamination of fetal bovine serum used for tissue culture: risks and concerns
Dev Biol Stand.
1991.
Abstract
Four viral contaminants have been routinely detected in unprocessed and commercial lots of fetal bovine serum: bacteriophage, infectious bovine rhinotracheitis, parainfluenza-3 and bovine viral diarrhea virus (BVDV). Of those, BVDV is consistently present in a majority of commercial lots of fetal bovine serum. Methods for BVDV detection and removal are reviewed. The tentative role of an unclassified pestivirus in microcephaly of infants has been reported. Its significance remains uncertain.
Similar articles
-
Bovine viral diarrhea virus contamination of nutrient serum, cell cultures and viral vaccines.Dev Biol Stand. 1991;75:177-81. Dev Biol Stand. 1991. PMID: 1665461
-
Viral contamination of bovine fetal lung cultures and bovine fetal serum.Am J Vet Res. 1980 Oct;41(10):1680-1. Am J Vet Res. 1980. PMID: 6261615
-
[Contamination of bovine fetal serum with bovine viral diarrhea virus].Rev Argent Microbiol. 2000 Jan-Mar;32(1):27-32. Rev Argent Microbiol. 2000. PMID: 10785940 Spanish.
-
Serum and serum substitutes: virus safety by inactivation or removal.Dev Biol Stand. 1999;99:131-8. Dev Biol Stand. 1999. PMID: 10404884 Review. No abstract available.
-
Detecting viruses in sera: methods used and their merits.Dev Biol Stand. 1999;99:51-9. Dev Biol Stand. 1999. PMID: 10404876 Review. No abstract available.
Cited by
-
A xenogeneic-free protocol for isolation and expansion of human adipose stem cells for clinical uses.PLoS One. 2013 Jul 9;8(7):e67870. doi: 10.1371/journal.pone.0067870. Print 2013. PLoS One. 2013. PMID: 23874459 Free PMC article.
-
Xeno-free trans-differentiation of adipose tissue-derived mesenchymal stem cells into glial and neuronal cells.Am J Stem Cells. 2019 Aug 15;8(2):38-51. eCollection 2019. Am J Stem Cells. 2019. PMID: 31523485 Free PMC article.
-
Serum-free media for the production of human mesenchymal stromal cells: a review.Cell Prolif. 2013 Dec;46(6):608-27. doi: 10.1111/cpr.12063. Epub 2013 Sep 30. Cell Prolif. 2013. PMID: 24118248 Free PMC article. Review.
-
Evaluation of platelet lysate as a substitute for FBS in explant and enzymatic isolation methods of human umbilical cord MSCs.Sci Rep. 2018 Aug 20;8(1):12439. doi: 10.1038/s41598-018-30772-4. Sci Rep. 2018. PMID: 30127445 Free PMC article.
-
Quality management overview for the production of a tissue-engineered human skin substitute in Malaysia.Stem Cell Res Ther. 2023 Oct 20;14(1):298. doi: 10.1186/s13287-023-03536-9. Stem Cell Res Ther. 2023. PMID: 37858277 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources