Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Aug;64(2):289-92.
doi: 10.1104/pp.64.2.289.

Influence of enol ether amino acids, inhibitors of ethylene biosynthesis, on aminoacyl transfer RNA synthetases and protein synthesis

A K Mattoo  1 , J D Anderson, E Chalutz, M Lieberman
Affiliations

Influence of enol ether amino acids, inhibitors of ethylene biosynthesis, on aminoacyl transfer RNA synthetases and protein synthesis

A K Mattoo et al. Plant Physiol. 1979 Aug.

Abstract

The analogs of rhizobitoxine, aminoethoxyvinylglycine (AVG) (l-2-amino-4-2'-aminoethoxy-trans-3 butenoic acid) and methoxyvinylglycine (MVG) (l-2-amino-4-methoxy-trans-3-butenoic acid), that are potent inhibitors of ethylene biosynthesis at 0.1 millimolar also inhibited protein synthesis and charging of tRNA especially at 1 millimolar and higher concentrations. The saturated analog of MVG inhibited ethylene synthesis while the saturated analog of AVG did not. Both saturated AVG and MVG inhibit methionyl- and leucyl-amino acyl-tRNA synthetase. Because of the inhibition of amino acid metabolism in plant tissues by these rhizobitoxine analogs caution is advised in interpreting the results obtained with concentrations of compounds above 0.1 millimolar.

PubMed Disclaimer

References

    1. Plant Physiol. 1977 Feb;59(2):158-60 - PubMed
    1. Plant Physiol. 1977 Apr;59(4):610-4 - PubMed
    1. Plant Physiol. 1965 Sep;40(5):927-30 - PubMed
    1. J Antibiot (Tokyo). 1972 Feb;25(2):122-7 - PubMed
    1. J Antibiot (Tokyo). 1974 Apr;27(4):229-33 - PubMed

LinkOut - more resources