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. 1981 Mar;67(3):467-9.
doi: 10.1104/pp.67.3.467.

Role of Glutamate-oxaloacetate Transaminase and Malate Dehydrogenase in the Regeneration of NAD for Glycine Oxidation by Spinach leaf Mitochondria

E P Journet  1 , M Neuburger, R Douce
Affiliations

Role of Glutamate-oxaloacetate Transaminase and Malate Dehydrogenase in the Regeneration of NAD for Glycine Oxidation by Spinach leaf Mitochondria

E P Journet et al. Plant Physiol. 1981 Mar.

Abstract

During glycine oxidation by spinach leaf mitochondria, oxygen consumption showed a strong and transient inhibition upon addition of oxaloacetate or aspartate plus alpha-ketoglutarate. During the course of the inhibition, aspartate and alpha-ketoglutarate were stoichiometrically transformed into malate and glutamate.It is concluded that oxaloacetate formed by transamination is reduced by the malate dehydrogenase, which allows the regeneration of NAD(+) for glycine oxidation and, thus, by-passes the respiratory chain. Efficiency of a malate-glutamate/aspartate-alpha-ketoglutarate shuttle upon illumination and under in vivo conditions is discussed.

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References

    1. Biochem Biophys Res Commun. 1972 May 12;47(3):619-24 - PubMed
    1. Biochim Biophys Acta. 1972 Aug 17;275(2):148-60 - PubMed
    1. Annu Rev Biochem. 1979;48:871-922 - PubMed
    1. Aust N Z J Obstet Gynaecol. 1980 Feb;20(1):32-4 - PubMed
    1. Plant Physiol. 1977 Oct;60(4):625-8 - PubMed

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