Evidence for the occurrence of, and possible physiological role for, cyanobacterial calmodulin
- PMID: 16663576
- PMCID: PMC1066866
- DOI: 10.1104/pp.75.1.222
Evidence for the occurrence of, and possible physiological role for, cyanobacterial calmodulin
Abstract
Phosphate uptake by the blue-green alga Oscillatoria limnetica Lemmerman is stimulated by micromolar concentrations of Ca(2+). The calmodulin antagonists 4-(3-[2(trifluoromethyl)phenylthiazin-10-yl]propyl)-1-piperazine ethanol-HCl and its monofluoro-analog inhibit orthophosphate uptake of Oscillatoria limnetica by over 97% implying involvement of calmodulin in this process. A calmodulin-like protein was quantitated in cell-free extracts from O. limnetica by radioimmunoassay.
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