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Comparative Study
. 1975 Jan-Feb;40(1):103-6.

[Hydrolysis of the methyl esters of the N-arylsulfonyl derivatives of L-arginine by thrombin and trypsin]

[Article in Russian]
S B Serebrianyĭ, V K Kibirev, A A Sereĭskaia, D M Fedoriak
  • PMID: 166707
Comparative Study

[Hydrolysis of the methyl esters of the N-arylsulfonyl derivatives of L-arginine by thrombin and trypsin]

[Article in Russian]
S B Serebrianyĭ et al. Biokhimiia. 1975 Jan-Feb.

Abstract

Trypsin- and thrombin-catalysed hydrolysis of the Nalpha-aryl-sulfonyl-L-arginine methyl esters was studied. Michaelis constants and kcat were determined. The hydrolysis of the substrates by trypsin appears to depend on the polar nature of substitutes. The thrombin- catalysed reaction was believed to be sensitive to steric effects of the introducted groups.

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