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Review
. 2006 Apr;34(2):65-71.
doi: 10.1249/00003677-200604000-00005.

Magnitude and time course of arterial vascular adaptations to inactivity in humans

Patricia C E de Groot  1 , Michiel W P Bleeker, Maria T E Hopman
Affiliations
Review

Magnitude and time course of arterial vascular adaptations to inactivity in humans

Patricia C E de Groot et al. Exerc Sport Sci Rev. 2006 Apr.

Abstract

We demonstrate that extensive arterial vascular adaptations occur within 3-8 wk of inactivity in humans. We put forth the hypothesis that the diameter decrease represents an adaptation to a lack of variation in peak shear stress. Furthermore, an enhanced flow-mediated dilation in deconditioned arteries implies that functional vascular adaptations to inactivity are not simply the inverse of adaptations to exercise.

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