Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006;10(2):211.
doi: 10.1186/cc4907.

Clinical review: specific aspects of acute renal failure in cancer patients

Affiliations
Review

Clinical review: specific aspects of acute renal failure in cancer patients

Michael Darmon et al. Crit Care. 2006.

Abstract

Acute renal failure (ARF) in cancer patients is a dreadful complication that causes substantial morbidity and mortality. Moreover, ARF may preclude optimal cancer treatment by requiring a decrease in chemotherapy dosage or by contraindicating potentially curative treatment. The pathways leading to ARF in cancer patients are common to the development of ARF in other conditions. However, ARF may also develop due to etiologies arising from cancer treatment, such as nephrotoxic chemotherapy agents or the disease itself, including post-renal obstruction, compression or infiltration, and metabolic or immunological mechanisms. This article reviews specific renal disease in cancer patients, providing a comprehensive overview of the causes of ARF in this setting, such as treatment toxicity, acute renal failure in the setting of myeloma or bone marrow transplantation.

PubMed Disclaimer

References

    1. Lanore JJ, Brunet F, Pochard F, Bellivier F, Dhainaut JF, Vaxelaire JF, Giraud T, Dreyfus F, Dreyfuss D, Chiche JD, et al. Hemo-dialysis for ARF in patients with hematologic malignancies. Crit Care Med. 1991;19:346–351. - PubMed
    1. Benoit DD, Depuydt PO, Vandewoude KH, Offner FC, Boterberg T, De Cock CA, Noens LA, Janssens AM, Decruyenaere JM. Outcome in critically ill medical patients treated with renal replacement therapy for acute renal failure: comparison between patients with and those without haematological malignancies. Nephrol Dial Transplant. 2005;20:552–558. doi: 10.1093/ndt/gfh637. - DOI - PubMed
    1. Azoulay E, Recher C, Alberti C, Soufir L, Leleu G, Le Gall JR, Fermand JP, Schlemmer B. Changing use of intensive care for hematological patients: the example of multiple myeloma. Intensive Care Med. 1999;25:1395–1401. doi: 10.1007/s001340051087. - DOI - PubMed
    1. Azoulay E, Moreau D, Alberti C, Leleu G, Adrie C, Barboteu M, Cottu P, Levy V, Le Gall JR, Schlemmer B. Predictors of short-term mortality in critically ill patients with solid malignancies. Intensive Care Med. 2000;26:1817–1823. doi: 10.1007/s001340051350. - DOI - PubMed
    1. Darmon M, Thiery G, Ciroldi M, de Miranda S, Galicier L, Raffoux E, Le Gall JR, Schlemmer B, Azoulay E. Intensive care in patients with newly diagnosed malignancies and a need for cancer chemotherapy. Crit Care Med. 2005;33:2488–2493. doi: 10.1097/01.CCM.0000181728.13354.0A. - DOI - PubMed

MeSH terms

Substances

LinkOut - more resources