Closing the GAP between polarity and vesicle transport
- PMID: 16678084
- DOI: 10.1016/j.cell.2006.04.011
Closing the GAP between polarity and vesicle transport
Abstract
How are tight junctions maintained? In this issue of Cell, Wells et al. (2006) provide intriguing evidence for a new pathway that links polarity proteins and vesicle transport to the maintenance of tight junctions, through the control of Cdc42 by Rich1, a GTPase-activating protein.
Comment on
-
A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.Cell. 2006 May 5;125(3):535-48. doi: 10.1016/j.cell.2006.02.045. Cell. 2006. PMID: 16678097
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
