A dedicated Wnt secretion factor
- PMID: 16678089
- DOI: 10.1016/j.cell.2006.04.018
A dedicated Wnt secretion factor
Abstract
The Wnt family of signaling proteins mediates cell-cell communication during development. In this issue of Cell, Bänziger et al. (2006) and Bartscherer et al. (2006) identify Wntless/Evi, a multipass transmembrane protein in the secretory pathway of Wnt-producing cells that promotes Wnt secretion.
Comment on
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Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells.Cell. 2006 May 5;125(3):509-22. doi: 10.1016/j.cell.2006.02.049. Cell. 2006. PMID: 16678095
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Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.Cell. 2006 May 5;125(3):523-33. doi: 10.1016/j.cell.2006.04.009. Cell. 2006. PMID: 16678096
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