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Comment
. 2006 May;3(5):305-7.
doi: 10.1016/j.cmet.2006.04.001.

Fat breakdown: a function for CGI-58 (ABHD5) provides a new piece of the puzzle

Chi-Liang Eric Yen  1 , Robert V Farese Jr
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Fat breakdown: a function for CGI-58 (ABHD5) provides a new piece of the puzzle

Chi-Liang Eric Yen et al. Cell Metab. 2006 May.
Free article

Abstract

The hydrolysis of fat stored in adipose tissues is crucial for providing energy during fasting and exercise, and dysregulation of fat breakdown may contribute to metabolic disease. In this issue of Cell Metabolism, report that CGI-58/ABHD5, a lipid-droplet-associated protein that is mutated in a rare disease characterized by excess lipid storage, activates adipose triglyceride lipase and thus may regulate fat mobilization.

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