Comment on

• Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany.

  Hinney A, Bettecken T, Tarnow P, Brumm H, Reichwald K, Lichtner P, Scherag A, Nguyen TT, Schlumberger P, Rief W, Vollmert C, Illig T, Wichmann HE, Schäfer H, Platzer M, Biebermann H, Meitinger T, Hebebrand J. Hinney A, et al. J Clin Endocrinol Metab. 2006 May;91(5):1761-9. doi: 10.1210/jc.2005-2056. Epub 2006 Feb 21. J Clin Endocrinol Metab. 2006. PMID: 16492696
• Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating.

  Lubrano-Berthelier C, Dubern B, Lacorte JM, Picard F, Shapiro A, Zhang S, Bertrais S, Hercberg S, Basdevant A, Clement K, Vaisse C. Lubrano-Berthelier C, et al. J Clin Endocrinol Metab. 2006 May;91(5):1811-8. doi: 10.1210/jc.2005-1411. Epub 2006 Feb 28. J Clin Endocrinol Metab. 2006. PMID: 16507637