Review
Signal transduction in yeast mating: receptors, transcription factors, and the kinase connection
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- PMID: 1668192
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Review
Signal transduction in yeast mating: receptors, transcription factors, and the kinase connection
Trends Genet.
1991 Nov-Dec.
Abstract
In the yeast Saccharomyces cerevisiae, peptide mating pheromones activate a signal transduction pathway that leads to cellular differentiation and cell division cycle arrest. It is now possible to trace the major events of this pathway. binding of pheromone to G-protein-coupled receptors activates a cascade of serine/threonine protein kinases that ultimately phosphorylate and increase the activity of an identified transcription factor.
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