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Review
. 2006 Jul:12 Suppl 3:1-7.
doi: 10.1111/j.1365-2516.2006.01253.x.

The pharmacokinetics of coagulation factors

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Review

The pharmacokinetics of coagulation factors

M Lee et al. Haemophilia. 2006 Jul.

Abstract

In this article, we provide a summary of the generally accepted approaches to the design and analysis of studies examining the pharmacokinetic (PK) profile of an infused coagulation factor in patients with a deficiency of one or more of these factors. Furthermore, we briefly review the known PK results for various commercially available coagulation factor preparations under single and continuous infusion.

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