Considerations for genomewide association studies in Parkinson disease

Comment

Richard H Myers. Am J Hum Genet. 2006 Jun.

. 2006 Jun;78(6):1081-2.

doi: 10.1086/504730.

No abstract available

Comment on

Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease.
Clarimon J, Scholz S, Fung HC, Hardy J, Eerola J, Hellstrom O, Chen CM, Wu YR, Tienari PJ, Singleton A. Clarimon J, et al. Am J Hum Genet. 2006 Jun;78(6):1082-4; author reply 1092-4. doi: 10.1086/504727. Am J Hum Genet. 2006. PMID: 16685660 Free PMC article. No abstract available.
Genomewide association, Parkinson disease, and PARK10.
Farrer MJ, Haugarvoll K, Ross OA, Stone JT, Milkovic NM, Cobb SA, Whittle AJ, Lincoln SJ, Hulihan MM, Heckman MG, White LR, Aasly JO, Gibson JM, Gosal D, Lynch T, Wszolek ZK, Uitti RJ, Toft M. Farrer MJ, et al. Am J Hum Genet. 2006 Jun;78(6):1084-8; author reply 1092-4. doi: 10.1086/504728. Am J Hum Genet. 2006. PMID: 16685661 Free PMC article. No abstract available.
No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.
Goris A, Williams-Gray CH, Foltynie T, Compston DA, Barker RA, Sawcer SJ. Goris A, et al. Am J Hum Genet. 2006 Jun;78(6):1088-90; author reply 1092-4. doi: 10.1086/504726. Am J Hum Genet. 2006. PMID: 16685662 Free PMC article. No abstract available.

1. Online Mendelian Inheritance in Man (OMIM), http://www.ncbi.nlm.nih.gov/entrez/Omim/ (for PD and LRRK2)

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1. Clarimon J, Scholz S, Fung H-C, Hardy J, Eerola J, Hellström O, Chen C-M, Wu Y-R, Tienari PJ, Singleton A (2006) Conflicting results regarding the semaphorin gene (SEMA5A) and the risk for Parkinson disease. Am J Hum Genet 78:1082–1084 (in this issue) - PMC - PubMed
1. Farrer MJ, Haugarvoll K, Ross OA, Stone JT, Milkovic NM, Cobb SA, Whittle AJ, Lincoln SJ, Hulihan MM, Heckman MG, White LR, Aasly JO, Gibson JM, Gosal D, Lynch T, Wszolek ZK, Uitti RJ, Toft M (2006) Genomewide association, Parkinson disease, and PARK10. Am J Hum Genet 78:1084–1088 (in this issue) - PMC - PubMed
1. Goris A, Williams-Gray CH, Foltynie T, Compston DAS, Barker RA, Sawcer SJ (2006) No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening. Am J Hum Genet 78:1088–1090 (in this issue) - PMC - PubMed
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