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. 2006 May;74(5):795-7.

First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon

Josiane Etang  1 , Etienne Fondjo, Fabrice Chandre, Isabelle Morlais, Cecile Brengues, Philippe Nwane, Mouhamadou Chouaibou, Hamadou Ndjemai, Frédéric Simard
Affiliations
  • PMID: 16687682

First report of knockdown mutations in the malaria vector Anopheles gambiae from Cameroon

Josiane Etang et al. Am J Trop Med Hyg. 2006 May.

Abstract

We report the first finding of the knockdown Leu-Phe and Leu-Ser mutations associated with resistance to pyrethroids and DDT insecticides in the malaria mosquito Anopheles gambiae from Cameroon. The Leu-Phe mutation was found in both the M and S molecular forms of An. gambiae. Importantly, two specimens of the S molecular form were found to carry both mutations in a heterozygous state.

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