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. 2006 Oct;100(10):986-8.
doi: 10.1016/j.trstmh.2006.02.004. Epub 2006 May 11.

Prevalence of Plasmodium falciparum cytochrome b gene mutations in isolates imported from Africa, and implications for atovaquone resistance

A Berry  1 , A Senescau, J Lelièvre, F Benoit-Vical, R Fabre, B Marchou, J F Magnaval
Affiliations

Prevalence of Plasmodium falciparum cytochrome b gene mutations in isolates imported from Africa, and implications for atovaquone resistance

A Berry et al. Trans R Soc Trop Med Hyg. 2006 Oct.

Abstract

The atovaquone resistance of malaria parasites correlates with mutations in the cytochrome b gene. We sequenced the Plasmodium falciparum cytochrome b gene of 135 African isolates. Our data showed a high mutation rate (8.9%); however, the risk of emergence spreading of atovaquone-resistant P. falciparum strains could be limited.

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