Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2006 May 13;332(7550):1150-2.
doi: 10.1136/bmj.332.7550.1150.

Common susceptibility genes for cancer: search for the end of the rainbow

Affiliations
Review

Common susceptibility genes for cancer: search for the end of the rainbow

Stuart G Baker et al. BMJ. .

Abstract

The human genome map has started a hunt to find common genes that are associated with cancer. But new research questions the likelihood of success.

PubMed Disclaimer

Figures

Figure 1
Figure 1
DNA chip analysis comparing gene expression in normal and cancerous prostate cells Credit: VERONIQUE BLANC AND QIN WANG/WELLCOME PHOTO LIBRARY

References

    1. Colhoun HM, McKeigue PM, Smith DS. Problems of reporting genetic associations with complex outcomes. Lancet 2003;361: 865-72. - PubMed
    1. Ioannidis JPA, Ntzani EE, Trikalinos TA, Contopoulos-Ioannidis DG. Replication validity of genetic association studies. Nature Genet 2001;29: 306-9. - PubMed
    1. Soto AM, Sonnenschein C. The somatic mutation theory of cancer: growing problems with the paradigm? BioEssays 2004;26: 1097-107. - PubMed
    1. Tisty TD, Hein PW. Know thy neighbor: stromal cells can contribute oncogenic signals. Curr Opin Genet Dev 2001;11: 54-9. - PubMed
    1. Allinen M, Beroukhim R, Cai L, Brennan C, Lahti-Domenici J, Huang H, et al. Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell 2004;6: 17-32. - PubMed

Publication types