Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Jul;12(1):162-5.
doi: 10.1128/iai.12.1.162-165.1975.

Herpes simplex virus infection in guinea pigs: an animal model for studying latent and recurrent herpes simplex virus infection

M Scriba

Herpes simplex virus infection in guinea pigs: an animal model for studying latent and recurrent herpes simplex virus infection

M Scriba. Infect Immun. 1975 Jul.

Abstract

Footpad infection of guinea pigs with herpes simplex virus led to an acute local inflammatory reaction, followed by a persistent latent infection of lumbosacral dorsal root ganglia. Spontaneous reactivation of the latent virus occurred, leading to recurrent lesions at the site of the initial infection. Clinical observations and virological studies during the acute latent and recurrent infection are reported.

PubMed Disclaimer

References

    1. Science. 1971 Aug 27;173(3999):843-5 - PubMed
    1. Nat New Biol. 1972 Feb 16;235(59):216-7 - PubMed
    1. Science. 1972 Oct 20;178(4058):306-7 - PubMed
    1. N Engl J Med. 1973 Mar 29;288(13):648-50 - PubMed
    1. N Engl J Med. 1974 Oct 17;291(16):828-30 - PubMed

MeSH terms

LinkOut - more resources