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Review
. 2006 Apr;8(5):1400-5.
doi: 10.1016/j.micinf.2005.12.009. Epub 2006 Feb 9.

The immunobiology of Acanthamoeba keratitis

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Free article
Review

The immunobiology of Acanthamoeba keratitis

Daniel W Clarke et al. Microbes Infect. 2006 Apr.
Free article

Abstract

Acanthamoeba spp. are free-living amoebae that cause Acanthamoeba keratitis, a blinding corneal infection. The innate immune apparatus is crucial for the resolution of the disease. With the exception of mucosal antibody, elements of the adaptive immune system fail to prevent infection or contribute to its resolution in experimental animals.

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