The immunobiology of Acanthamoeba keratitis
- PMID: 16697233
- DOI: 10.1016/j.micinf.2005.12.009
The immunobiology of Acanthamoeba keratitis
Abstract
Acanthamoeba spp. are free-living amoebae that cause Acanthamoeba keratitis, a blinding corneal infection. The innate immune apparatus is crucial for the resolution of the disease. With the exception of mucosal antibody, elements of the adaptive immune system fail to prevent infection or contribute to its resolution in experimental animals.
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