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Case Reports
. 2006 May-Jun;15(3):157-60.
doi: 10.1016/j.carpath.2006.02.003.

Fatal cor pulmonale caused by pulmonary tumor microembolism in a patient with occult gastric cancer

Domenico Corradi  1 , Francesca Mormandi, Giulia Tanzi, Roberto Ricci, Paola Bini, Sara Giuliotti, Maurizio Zompatori
Affiliations
Case Reports

Fatal cor pulmonale caused by pulmonary tumor microembolism in a patient with occult gastric cancer

Domenico Corradi et al. Cardiovasc Pathol. 2006 May-Jun.

Abstract

Background: A fatal pulmonary tumor microembolism is rarely caused by an occult gastric cancer.

Methods and results: We report the case of a 40-year-old woman who died after 3 days of progressive dyspnea, cough, and pulmonary hypertension. Postmortem examination demonstrated the presence of an occult diffuse-type gastric carcinoma, which had caused emboli in about 80% of small pulmonary arteries and arterioles. Despite an interatrial defect in the fossa ovalis, no parenchymal metastases were documented.

Conclusion: Pulmonary tumor microembolism may be suspected in patients complaining of unexplained progressive dyspnea and who develop acute or subacute cor pulmonale.

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