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Review
. 2006 Jun;49(6):987-97.
doi: 10.1016/j.eururo.2006.02.059. Epub 2006 Mar 20.

A critical analysis of nonsurgical treatment of Peyronie's disease

Ekkehard W Hauck  1 , Thorsten Diemer, Hans U Schmelz, Wolfgang Weidner
Affiliations
Review

A critical analysis of nonsurgical treatment of Peyronie's disease

Ekkehard W Hauck et al. Eur Urol. 2006 Jun.

Abstract

Objective: Because the efficacy of nonsurgical therapy of Peyronie's disease is controversial, this review analyses the current status of conservative therapy of Peyronie's disease.

Method: A systematic survey on results of studies published as original papers in peer-reviewed journals is provided.

Results: Oral drug therapies include potassium para-aminobenzoate (Potaba), vitamin E, colchicine, tamoxifen, propoleum, acetyl-L-carnitine, and propionyl-L-carnitine. Verapamil, interferon-alpha2a and interferon-alpha2b, collagenase, cortisone, hyaluronidase, and superoxide dismutase are considered intralesional therapies that have had various degrees of success. Other treatments include local gels, iontophoresis, extracorporeal shock wave therapy, and radiation.

Conclusion: This review analyses the current status of the conservative therapy of Peyronie's disease, because the efficacy of the nonsurgical therapy is controversial.

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