Maternal diabetes and the fetal heart
- PMID: 16698822
- PMCID: PMC1861084
- DOI: 10.1136/hrt.2005.083840
Maternal diabetes and the fetal heart
Abstract
Maternal diabetes mellitus significantly affects the fetal heart and fetal-placental circulation in both structure and function. The influence of pre-conceptional diabetes begins during embryonic development in the first trimester, with altered cardiac morphogenesis and placental development. It continues to have an influence on the fetal circulation through the second and third trimesters and into the perinatal and neonatal period.
Comment on
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Increased periconceptual maternal glycated haemoglobin in diabetic mothers reduces fetal long axis cardiac function.Heart. 2006 Aug;92(8):1125-30. doi: 10.1136/hrt.2005.076885. Epub 2005 Nov 8. Heart. 2006. PMID: 16278273 Free PMC article.
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