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Review
. 2006 Mar;65(1):47-51.
doi: 10.4081/monaldi.2006.587.

Lung stem cell update: promise and controversy

I P Neuringer  1 , S H Randell
Affiliations
Review

Lung stem cell update: promise and controversy

I P Neuringer et al. Monaldi Arch Chest Dis. 2006 Mar.

Abstract

Currently, there is great enthusiasm about potential stem cell therapies for intractable diseases. We previously reviewed the topic of stem cells in lung injury and repair, including the role of endogenous, tissue (somatic) stem cells and the contribution of circulating cells to the lung parenchyma. Our purpose here is to provide a concise update in this fast-moving field. New information and ongoing debate focus attention on basic issues in lung stem cell biology and highlight the need for additional studies to establish the feasibility of cell therapies to prevent or treat lung diseases.

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