doi: 10.1038/sj.jid.5700357.
PSORS1: linking genetics and immunology
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- PMID: 16702966
- DOI: 10.1038/sj.jid.5700357
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PSORS1: linking genetics and immunology
J Invest Dermatol.
2006 Jun.
Free article
Abstract
Previous studies have localized the psoriasis susceptibility 1 (PSORS1) locus to the proximal major histocompatibility complex class I region, but approximately a dozen genes in the candidate region have thus far been genetically inseparable. According to a team of researchers in the United States and Germany, the primary genetic association has now been worked out, implicating HLA-Cw6 "after all." The results integrate genetics and immunology, further reinforcing our emerging understanding of psoriasis.
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