Comparative Study
doi: 10.1016/0140-6736(91)92161-t.
Lipoprotein(a) reduction by N-acetylcysteine
Affiliations
- PMID: 1670844
- DOI: 10.1016/0140-6736(91)92161-t
Item in Clipboard
Comparative Study
Lipoprotein(a) reduction by N-acetylcysteine
Lancet.
.
Abstract
Lipoprotein(a), a complex of low-density lipoprotein linked by disulphide bridges with apo(a), is associated with atherosclerotic disease when present at very high plasma concentrations. In vitro, N-acetylcysteine (NAC) dissociates this complex. In two patients with high Lp(a) levels NAC lowered plasma Lp(a) from 58 to 20 mg/dl and from 59 to 18 mg/dl: reductions of this order have not hitherto been achieved either by drugs or by diet.
Comment in
-
N-acetylcysteine and lipoprotein(a).Lancet. 1992 Jan 11;339(8785):126-7. doi: 10.1016/0140-6736(92)91039-b. Lancet. 1992. PMID: 1345854 No abstract available.
-
Lipoprotein(a) reduction by N-acetylcysteine.Lancet. 1991 Mar 16;337(8742):672-3. doi: 10.1016/0140-6736(91)92484-j. Lancet. 1991. PMID: 1672008 No abstract available.
-
N-acetylcysteine and immunoreactivity of lipoprotein(a).Lancet. 1991 May 11;337(8750):1159. doi: 10.1016/0140-6736(91)92824-l. Lancet. 1991. PMID: 1674031 No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
