Review
doi: 10.1042/BST0340377.
Phosphatidylinositol-transfer protein and its homologues in yeast
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- PMID: 16709166
- DOI: 10.1042/BST0340377
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Review
Phosphatidylinositol-transfer protein and its homologues in yeast
Biochem Soc Trans.
2006 Jun.
Abstract
Yeast Sec14p acts as a phosphatidylinositol/phosphatidylcholine-transfer protein in vitro. In vivo, it is essential in promoting Golgi secretory function. Products of five genes named SFH1-SFH5 (Sec Fourteen Homologues 1-5) exhibit significant sequence homology to Sec14p and together they form the Sec14p family of lipid-transfer proteins. It is a diverse group of proteins with distinct subcellular localizations and varied physiological functions related to lipid metabolism and membrane trafficking.
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