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Review
. 2006 Jun;2(6):284-7.
doi: 10.1038/nchembio0606-284.

Making carbon-nitrogen bonds in biological and chemical synthesis

Ryan Hili  1 , Andrei K Yudin
Affiliations
Review

Making carbon-nitrogen bonds in biological and chemical synthesis

Ryan Hili et al. Nat Chem Biol. 2006 Jun.

Abstract

The function of many biologically active molecules requires the presence of carbon-nitrogen bonds in strategic positions. The biosynthetic pathways leading to such bonds can be bypassed through chemical synthesis to synthesize natural products more efficiently and also to generate the molecular diversity unavailable in nature.

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