Eukaryotic transcription: what does it mean for a gene to be 'on'?
- PMID: 16713947
- DOI: 10.1016/j.cub.2006.04.014
Eukaryotic transcription: what does it mean for a gene to be 'on'?
Abstract
Until recently, transcription could only be observed by measuring mRNA production of cell populations, thus obscuring the kinetics at the level of individual transcription events. A new study now shows that eukaryotic transcription, visualised in individual living cells, occurs in bursts -- much as it does in prokaryotes.
Comment on
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Transcriptional pulsing of a developmental gene.Curr Biol. 2006 May 23;16(10):1018-25. doi: 10.1016/j.cub.2006.03.092. Curr Biol. 2006. PMID: 16713960 Free PMC article.
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